Do you ever feel a burning or uneasy sensation in your stomach after eating? That occasional discomfort can disrupt your day and make you dread meals. Many people turn to herbs for gentle, natural relief. Deglycyrrhizinated licorice (DGL) is one such herb that has gained attention for its ability to support the stomach lining and promote digestive comfort. In this guide, we will explain what DGL licorice is, how it works, and what to look for when choosing a supplement.

1
Best Seller

Natural Factors DGL Licorice 400 mg

Natural Factors
9.9 /10
AI Score
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Natural Factors DGL Licorice 400 mg chewable tablets offer a gentle, plant-based way to support digestive health by protecting the stomach lining. Ideal for those seeking a sugar-free, vegan supplement to ease occasional discomfort.
Pros & Cons

Pros

  • Specialized DGL formulation protects stomach lining without side effects of regular licorice
  • Highly rated for digestive support, with a 4.9-star average from users
  • Clean label: vegan, gluten-free, dairy-free, and free from major allergens
  • Rigorous third-party testing for safety and purity

Cons

  • Chewable tablets may not be suitable for those who dislike licorice flavor
  • Requires consistent pre-meal timing for best results
  • Limited to digestive health benefits; not a multi-purpose supplement
Detailed Review

Natural Factors DGL Licorice 400 mg chewable tablets are a targeted digestive supplement designed for anyone seeking gentle, natural support for stomach and intestinal health. Unlike standard licorice root, this deglycyrrhizinated formula (DGL) removes glycyrrhizin, making it safe for long-term use without affecting blood pressure. It’s an excellent choice for individuals with occasional indigestion, heartburn, or those wanting to maintain a healthy gut lining.

The standout feature is the chewable form, which allows the active compounds to begin soothing the stomach immediately. Each tablet delivers 400 mg of DGL licorice extract, and taking one to three tablets 20 minutes before meals helps reinforce the mucosal barrier. Users report noticeable relief from discomfort, especially when taken consistently. The natural sweetness from licorice makes the tablets palatable, though the flavor may take some getting used to.

Build quality is impressive: Natural Factors, a family-owned company for over six decades, subjects every batch to ISURA third-party testing for more than 800 contaminants. The tablets are vegan, free from gluten, dairy, soy, and GMOs, which aligns with clean-label preferences. The 180-count bottle offers a two- to three-month supply at the recommended dosage, providing good value for daily use.

One potential drawback is the specific taste of licorice, which some may find strong or medicinal. Additionally, the product’s benefits are focused on digestive support; it’s not a broad-spectrum supplement. Users with severe conditions should consult a healthcare professional before use. However, for its intended purpose, the DGL formula stands out as a targeted, effective solution.

Overall, Natural Factors DGL Licorice 400 mg chewable tablets earn high marks for purity, efficacy, and clean formulation. If you’re looking for a gentle digestive aid that supports your stomach lining without additives or allergens, this supplement is a trustworthy choice. Its strong ratings and rigorous testing make it a top pick in the licorice root category.

2
Editor's Pick

Amen Leaky Gut Supplement with L-Glutamine

Amen
9.9 /10
AI Score
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Amen Leaky Gut is a comprehensive vegan supplement that combines L-glutamine, DGL licorice, zinc, and a 10 billion CFU probiotic blend to support intestinal lining health and digestive balance. It is ideal for individuals seeking a multi-ingredient gut health formula in a convenient capsule form.
Pros & Cons

Pros

  • All-in-one formula targeting multiple aspects of gut health.
  • High-potency probiotic blend with four shelf-stable strains.
  • Vegan, non-GMO, and allergen-friendly ingredient profile.
  • Manufactured in a cGMP-certified USA facility.
  • Contains organic and fermented prebiotics to enhance probiotic effectiveness.

Cons

  • As a newer product, real-world feedback on long-term efficacy is still limited.
  • DGL licorice root may interact with certain medications, so medical consultation is advised.
  • 90 capsules per bottle may require frequent repurchase for users needing higher daily doses.
Detailed Review

The Amen Leaky Gut supplement is a thoughtfully designed formula for those seeking comprehensive digestive support. It combines L-glutamine, DGL licorice, zinc, organic turmeric, and marshmallow root in a convenient vegan capsule, making it easy to add to your daily routine.

What sets this supplement apart is its inclusion of 10 billion CFU of shelf-stable probiotics from four distinct strains, along with organic prebiotics like apple cider vinegar and ginger. This blend works synergistically to support a balanced gut microbiome and a healthy intestinal lining, addressing both immediate and long-term gut health needs.

The formulation is built around high-quality ingredients, including L-glutamine for gut barrier repair and DGL licorice root that has been processed to remove glycyrrhizin, minimizing the risk of side effects. It is also vegan, non-GMO, and free from major allergens, which broadens its appeal to health-conscious consumers with dietary restrictions.

One potential drawback is the limited real-world feedback available, making it difficult to gauge long-term results. Additionally, the 90-capsule bottle may not offer the best value for those requiring higher daily doses, and the licorice root extract, even in DGL form, might interact with certain medications. Consulting a healthcare provider before use is recommended.

Overall, Amen Leaky Gut is a well-rounded, high-quality supplement that delivers a comprehensive approach to gut health. Its clean ingredient profile, probiotic blend, and supportive nutrients make it a strong candidate for anyone looking to fortify their digestive system, provided they are mindful of serving size and potential interactions.

3
Limited Time

Zazzee USDA Organic DGL Licorice 20:1 Extract

Zazzee
9.9 /10
AI Score
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This potent organic DGL licorice extract delivers a 20:1 concentration in vegan capsules, offering a reliable 4 month supply for digestive support. Ideal for users seeking a high potency, certified organic supplement.
Pros & Cons

Pros

  • High potency 20:1 extract for maximum effectiveness per capsule.
  • USDA Organic certified for premium quality.
  • Long lasting supply with 120 capsules per bottle.
  • Vegan and allergen free, suitable for many dietary needs.
  • Produced in the USA with stringent quality control.

Cons

  • No customer reviews yet to validate real world efficacy.
  • Results may vary and consistent use is necessary for best outcomes.
  • Not suitable for individuals with certain medical conditions or those taking specific medications without professional advice.
Detailed Review

The Zazzee USDA Organic DGL Licorice 20:1 Extract is a high potency digestive supplement designed for those seeking natural, concentrated support. Ideal for individuals with occasional stomach discomfort or those wanting to maintain a healthy digestive lining, this extract offers a powerful alternative to standard powders.

Its standout feature is the 20:1 extract ratio, meaning each capsule delivers 20 times the active compounds of regular DGL powder. This allows for a simpler regimen, requiring just one capsule per serving. The USDA Organic certification further elevates its appeal, ensuring the product is free from synthetic pesticides and contaminants, with all ingredients including the capsule meeting organic standards.

Manufactured in a US based GMP certified facility, the build quality is excellent. The capsules are fully vegan and free from common allergens like gluten, soy, and dairy, making them accessible to a wide audience. The 120 count supply lasts for four months, offering substantial value for a premium organic product.

One potential drawback is the absence of customer reviews, which means individual experiences are yet to be widely shared. Additionally, as with any licorice supplement, users with hypertension or kidney issues should consult a healthcare provider before use. The product is designed for consistent, long term use to achieve optimal results.

Overall, Zazzee delivers a potent, pure, and ethically produced DGL supplement that stands out in the crowded market. For those prioritizing organic certification and high extract potency, this is an excellent choice that combines effectiveness with peace of mind.

4
Top Rated

Vitamatic DGL Licorice 10:1 Extract 380mg

Vitamatic
9.8 /10
AI Score
AI score rating is a scoring system developed by our experts. The score is from 0 to 10 based on the data collected by the AI tool. This score doesn't impact from any manufacturer or sales agent websites. Learn more ›
This concentrated DGL licorice supplement delivers 380mg of 10:1 extract with L-glycine to help soothe the digestive tract and support the stomach's protective mucus lining. Ideal for vegetarians and anyone looking for a clean, plant-based gut support formula.
Pros & Cons

Pros

  • High-potency 10:1 extract provides a concentrated dose in a single capsule
  • Clean, allergen-friendly formula with no artificial ingredients
  • Plant-based capsules suit vegetarian and vegan lifestyles
  • Manufactured in a GMP-compliant facility in the USA
  • Large 200-count bottle delivers excellent value for daily supplementation

Cons

  • Contains licorice root, which may not be suitable for individuals with high blood pressure or kidney issues
  • L-glycine may cause mild drowsiness or stomach upset in sensitive individuals
Detailed Review

The Vitamatic DGL Licorice 10:1 Extract supplement is a targeted herbal formula designed for individuals seeking digestive comfort. With 380mg of concentrated licorice root extract per capsule, it pairs L-glycine to help support the stomach's natural mucus lining. This makes it a suitable choice for those with occasional indigestion or gut sensitivity.

The 10:1 extract ratio means you're getting a highly concentrated dose of the active compounds found in deglycyrrhizinated licorice. Combined with L-glycine, an amino acid known for its calming properties, this capsule aims to promote a healthy intestinal environment. Users on similar DGL formulas often report soothing relief after meals.

Each bottle contains 200 plant-based, vegetarian capsules, free from sugar, gluten, soy, corn, wheat, and artificial additives. Manufactured in the USA under strict GMP standards, the formula is non-GMO and designed for clean, consistent supplementation. The capsules are easy to swallow and hold their potency well.

As with any licorice-derived supplement, DGL is not recommended for individuals with high blood pressure, kidney disease, or those taking certain medications. While the product is concentrated, new users may need to assess their tolerance and start with a single capsule. Potential side effects like drowsiness from L-glycine are uncommon but possible.

Overall, the Vitamatic DGL Licorice 10:1 Extract with L-Glycine offers a solid, clean, and value-packed option for anyone looking to support their digestive system naturally. Its thoughtful ingredient list and high concentration make it a competitive choice in the herbal supplement space. We recommend it for health-conscious buyers seeking an accessible gut support formula.

6

IIEltruiom DGL Gummies with Zinc Carnosine & Aloe

IIEltruiom
9.7 /10
AI Score
AI score rating is a scoring system developed by our experts. The score is from 0 to 10 based on the data collected by the AI tool. This score doesn't impact from any manufacturer or sales agent websites. Learn more ›
The IIEltruiom DGL Gummies combine DGL, zinc carnosine, aloe vera, ginger, and apple cider vinegar in a tasty, vegan-friendly gummy designed to support daily stomach comfort and digestive balance. Ideal for adults seeking a convenient, pleasant-tasting digestive supplement.
Pros & Cons

Pros

  • Combines multiple digestive-supporting ingredients in one formula
  • Pleasant mixed berry taste with no added sugar
  • Vegan and gelatin-free, suitable for plant-based diets
  • Convenient gummy format is easy to take daily
  • Manufactured in a cGMP-compliant facility

Cons

  • No customer reviews yet, so real-world feedback is limited
  • Gummies may not be suitable for those avoiding fruit flavors or natural sweeteners
  • Individual results may vary, as with any supplement
Detailed Review

The IIEltruiom DGL Gummies are a thoughtfully formulated digestive supplement designed for adults seeking gentle, daily support for stomach comfort and digestive balance. Combining deglycyrrhizinated licorice (DGL), zinc carnosine, sodium alginate, aloe vera, ginger, and apple cider vinegar, this gummy offers a multi-faceted approach to digestive wellness.

What sets these gummies apart is the synergistic blend of DGL and zinc carnosine, two ingredients often used in digestive health formulas. DGL is known for its soothing properties, while zinc carnosine supports stomach lining health and overall digestive comfort. The addition of aloe vera, ginger, and apple cider vinegar further enhances the formula, providing a comprehensive solution for those with occasional digestive discomfort.

The gummies are crafted with a delicious mixed berry flavor and contain no added sugar, making them a pleasant alternative to chalky chewables or hard-to-swallow capsules. They are vegan-friendly and gelatin-free, catering to a wide range of dietary preferences. The product is manufactured in a cGMP-compliant facility, ensuring quality and consistency.

While the product holds great promise, it currently has no customer reviews, so real-world performance is yet to be verified. Additionally, as with any supplement, individual results may vary, and it is always advisable to consult a healthcare professional before starting a new regimen, especially for those with underlying health conditions.

Overall, the IIEltruiom DGL Gummies offer a convenient and tasty way to support digestive health daily. With their comprehensive ingredient profile and vegan-friendly formulation, they are a solid choice for adults looking to enhance their digestive wellness routine.

Buying Guide

Form Matters: Chewable vs. Capsule

DGL licorice is often available as chewable tablets or capsules. Chewable forms are believed to mix with saliva and coat the throat and stomach more effectively. Capsules offer convenience and precise dosing. Choose based on your preference and lifestyle.

Potency and Standardization

Look for a product that is deglycyrrhizinated to remove glycyrrhizin, a compound that can raise blood pressure. A standardized extract ensures consistent levels of active compounds.

Additional Soothing Ingredients

Many DGL formulas combine with other gut-friendly herbs like slippery elm, marshmallow root, or aloe vera. These can enhance the soothing effect. Check the label for complementary ingredients that align with your needs. For more on herbal digestive aids, see our guide on peppermint oil for digestive support.

Brand Reputation and Quality Assurance

Choose a brand that follows good manufacturing practices and uses third-party validation. AMPJOINT is a reputable name in the supplement industry, known for quality and transparency.

Final Thoughts

Its carefully formulated blend and quality assurance make it ideal for those seeking daily digestive comfort. For a different approach, you might also explore ginger supplements for digestion.

Frequently Asked Questions

How does DGL licorice work for digestion? DGL licorice helps protect the stomach lining by increasing mucus production and promoting healthy blood flow to the digestive tract. It may reduce irritation from stomach acid.

Is DGL licorice safe for long-term use? Yes, DGL is considered safe for extended use because the glycyrrhizin has been removed. However, consult your healthcare provider before starting any new supplement regimen.

Can DGL licorice help with heartburn? Many people find DGL effective for occasional heartburn and acid reflux. It works by coating the esophagus and stomach, providing a barrier against acid. For more on digestive aids, see our peppermint oil guide.

When is the best time to take DGL licorice? For optimal results, take DGL licorice 20 to 30 minutes before meals or at the onset of discomfort. Follow the dosage instructions on the product label.