Acid reflux can disrupt your daily life, leaving you searching for gentle yet effective digestive support. Deglycyrrhizinated licorice (DGL) has emerged as a natural option to soothe stomach discomfort and support mucosal integrity. In this guide, we review the best DGL licorice supplements for acid reflux relief in 2026, comparing top brands like Natural Factors, Pure Encapsulations, and Nutricost. For more digestive health insights, visit our Digestive Health category.
Pros
- Specialized DGL formulation protects stomach lining without side effects of regular licorice
- Highly rated for digestive support, with a 4.9-star average from users
- Clean label: vegan, gluten-free, dairy-free, and free from major allergens
- Rigorous third-party testing for safety and purity
Cons
- Chewable tablets may not be suitable for those who dislike licorice flavor
- Requires consistent pre-meal timing for best results
- Limited to digestive health benefits; not a multi-purpose supplement
Natural Factors DGL Licorice 400 mg chewable tablets are a targeted digestive supplement designed for anyone seeking gentle, natural support for stomach and intestinal health. Unlike standard licorice root, this deglycyrrhizinated formula (DGL) removes glycyrrhizin, making it safe for long-term use without affecting blood pressure. It’s an excellent choice for individuals with occasional indigestion, heartburn, or those wanting to maintain a healthy gut lining.
The standout feature is the chewable form, which allows the active compounds to begin soothing the stomach immediately. Each tablet delivers 400 mg of DGL licorice extract, and taking one to three tablets 20 minutes before meals helps reinforce the mucosal barrier. Users report noticeable relief from discomfort, especially when taken consistently. The natural sweetness from licorice makes the tablets palatable, though the flavor may take some getting used to.
Build quality is impressive: Natural Factors, a family-owned company for over six decades, subjects every batch to ISURA third-party testing for more than 800 contaminants. The tablets are vegan, free from gluten, dairy, soy, and GMOs, which aligns with clean-label preferences. The 180-count bottle offers a two- to three-month supply at the recommended dosage, providing good value for daily use.
One potential drawback is the specific taste of licorice, which some may find strong or medicinal. Additionally, the product’s benefits are focused on digestive support; it’s not a broad-spectrum supplement. Users with severe conditions should consult a healthcare professional before use. However, for its intended purpose, the DGL formula stands out as a targeted, effective solution.
Overall, Natural Factors DGL Licorice 400 mg chewable tablets earn high marks for purity, efficacy, and clean formulation. If you’re looking for a gentle digestive aid that supports your stomach lining without additives or allergens, this supplement is a trustworthy choice. Its strong ratings and rigorous testing make it a top pick in the licorice root category.
Pros
- High potency 20:1 extract for maximum effectiveness per capsule.
- USDA Organic certified for premium quality.
- Long lasting supply with 120 capsules per bottle.
- Vegan and allergen free, suitable for many dietary needs.
- Produced in the USA with stringent quality control.
Cons
- No customer reviews yet to validate real world efficacy.
- Results may vary and consistent use is necessary for best outcomes.
- Not suitable for individuals with certain medical conditions or those taking specific medications without professional advice.
The Zazzee USDA Organic DGL Licorice 20:1 Extract is a high potency digestive supplement designed for those seeking natural, concentrated support. Ideal for individuals with occasional stomach discomfort or those wanting to maintain a healthy digestive lining, this extract offers a powerful alternative to standard powders.
Its standout feature is the 20:1 extract ratio, meaning each capsule delivers 20 times the active compounds of regular DGL powder. This allows for a simpler regimen, requiring just one capsule per serving. The USDA Organic certification further elevates its appeal, ensuring the product is free from synthetic pesticides and contaminants, with all ingredients including the capsule meeting organic standards.
Manufactured in a US based GMP certified facility, the build quality is excellent. The capsules are fully vegan and free from common allergens like gluten, soy, and dairy, making them accessible to a wide audience. The 120 count supply lasts for four months, offering substantial value for a premium organic product.
One potential drawback is the absence of customer reviews, which means individual experiences are yet to be widely shared. Additionally, as with any licorice supplement, users with hypertension or kidney issues should consult a healthcare provider before use. The product is designed for consistent, long term use to achieve optimal results.
Overall, Zazzee delivers a potent, pure, and ethically produced DGL supplement that stands out in the crowded market. For those prioritizing organic certification and high extract potency, this is an excellent choice that combines effectiveness with peace of mind.
Pros
- Potent 10:1 extract means a little goes a long way.
- Ample 120-serving supply for extended use without frequent repurchasing.
- Manufactured in a certified facility with third-party testing for purity.
- Gluten-free and non-GMO, suitable for various dietary needs.
- Trusted brand with transparent quality processes.
Cons
- New product with no customer reviews yet, so long-term feedback is limited.
- Capsules may be large for some users; check if you have difficulty swallowing pills.
- No flavored or chewable options available for those who dislike capsules.
Nutricost DGL Extract offers a potent 10:1 concentration of deglycyrrhizinated licorice root, delivering 500mg of extract per capsule. This supplement is designed for individuals seeking digestive support, particularly those who prefer a high-potency, standardized herbal extract. The 120-capsule bottle provides a two-month supply, making it convenient for daily use.
The standout feature is the 10:1 extraction ratio, which means each capsule contains the equivalent of 5,000mg of raw licorice root. This concentration enhances the beneficial compounds while removing glycyrrhizin, a component that can cause side effects. Real-world performance is backed by Nutricost's commitment to third-party testing and NSF-certified manufacturing, ensuring consistent potency and purity.
Build quality is solid: the capsules are standard size and the bottle is practical for storage. The product is gluten-free and non-GMO, appealing to clean-label advocates. However, as with any supplement, individual results may vary, and those with specific health conditions should consult a healthcare professional before use.
A potential drawback is the lack of customer reviews, which makes it harder to gauge broad user satisfaction. Additionally, some users may find the capsules large or prefer liquid or chewable alternatives. However, for those who prioritize potency and rigorous quality control, this is a compelling choice.
Overall, Nutricost DGL Extract stands out for its high concentration and transparent manufacturing. It is an excellent option for anyone looking for a reliable, potent digestive support supplement. The value is strong given the serving count, and the brand's reputation adds trust. If you are comfortable with capsules and want a concentrated extract, this product deserves consideration.
Pros
- Combines multiple digestive-supporting ingredients in one formula
- Pleasant mixed berry taste with no added sugar
- Vegan and gelatin-free, suitable for plant-based diets
- Convenient gummy format is easy to take daily
- Manufactured in a cGMP-compliant facility
Cons
- No customer reviews yet, so real-world feedback is limited
- Gummies may not be suitable for those avoiding fruit flavors or natural sweeteners
- Individual results may vary, as with any supplement
The IIEltruiom DGL Gummies are a thoughtfully formulated digestive supplement designed for adults seeking gentle, daily support for stomach comfort and digestive balance. Combining deglycyrrhizinated licorice (DGL), zinc carnosine, sodium alginate, aloe vera, ginger, and apple cider vinegar, this gummy offers a multi-faceted approach to digestive wellness.
What sets these gummies apart is the synergistic blend of DGL and zinc carnosine, two ingredients often used in digestive health formulas. DGL is known for its soothing properties, while zinc carnosine supports stomach lining health and overall digestive comfort. The addition of aloe vera, ginger, and apple cider vinegar further enhances the formula, providing a comprehensive solution for those with occasional digestive discomfort.
The gummies are crafted with a delicious mixed berry flavor and contain no added sugar, making them a pleasant alternative to chalky chewables or hard-to-swallow capsules. They are vegan-friendly and gelatin-free, catering to a wide range of dietary preferences. The product is manufactured in a cGMP-compliant facility, ensuring quality and consistency.
While the product holds great promise, it currently has no customer reviews, so real-world performance is yet to be verified. Additionally, as with any supplement, individual results may vary, and it is always advisable to consult a healthcare professional before starting a new regimen, especially for those with underlying health conditions.
Overall, the IIEltruiom DGL Gummies offer a convenient and tasty way to support digestive health daily. With their comprehensive ingredient profile and vegan-friendly formulation, they are a solid choice for adults looking to enhance their digestive wellness routine.
Pros
- Comprehensive herbal formula targeting gut lining health
- Clean, allergen-free ingredient profile suitable for sensitive individuals
- Vegan and gluten-free certification meets dietary restrictions
- Trusted brand with rigorous quality testing and expert formulation
Cons
- Some users may prefer tablets over capsules for ease of swallowing
- Limited user reviews available to gauge real-world effectiveness
- Higher price point compared to basic licorice root supplements
Pure Encapsulations DGL Plus is a targeted herbal supplement designed to support the health of your stomach lining and gastrointestinal tract. It combines deglycyrrhizinated licorice (DGL) with soothing botanicals like aloe vera, marshmallow root, and slippery elm bark. This makes it an excellent choice for individuals looking for gentle, plant-based digestive support, especially those with sensitive stomachs or dietary restrictions.
The standout feature of this formula is its use of DGL, which provides the benefits of licorice root without the compound glycyrrhizin, known to affect blood pressure. The addition of aloe vera, marshmallow root, and slippery elm bark further enhances mucosal comfort and soothes the digestive tract. While there are no user reviews available yet, the ingredient profile is well-regarded in herbal medicine for gut lining support.
In terms of design and build quality, Pure Encapsulations maintains a reputation for purity and potency. The capsules are vegan and gluten-free, and the product is free from common allergens, artificial ingredients, and GMOs. Each batch is tested to verify quality, giving users confidence in what they are consuming. The 60-count bottle offers a convenient one-month supply at the recommended dosage.
A potential drawback is the lack of consumer feedback, making it harder to assess real-world performance. Additionally, some users may find the price slightly higher than basic licorice root supplements, though the premium blend and rigorous testing justify the cost. The capsule form may not be ideal for those who prefer chewables or powders.
Overall, Pure Encapsulations DGL Plus is a well-formulated, clean-label supplement for those seeking targeted gut lining support. If you value quality ingredients and a brand committed to purity, this product is a solid choice. However, if you have specific health concerns, consulting a healthcare professional before use is always recommended.
Buying Guide
Potency and Extract Ratio
The potency of a DGL supplement is often indicated by its extract ratio, such as 10:1 or 20:1. A higher ratio means a more concentrated dose, which can be beneficial for those seeking stronger support. For daily maintenance, a standard 400 mg chewable tablet may suffice, while concentrated extracts offer value for long-term use.
Purity and Organic Certification
Since licorice root can absorb contaminants from soil, choosing an organic or rigorously purified product is crucial. Look for third-party certifications like USDA Organic or verification for heavy metals and pesticides. Brands like Zazzee emphasize organic sourcing to ensure a clean supplement.
Form and Ease of Use
DGL supplements come as chewable tablets, capsules, or gummies. Chewable tablets are ideal for those who dislike swallowing pills, while gummies offer a tasty alternative. If you travel often, consider a portable option like daily digestive health supplements that fit easily into your routine.
Brand Reputation and Quality Assurance
Trustworthy brands invest in quality control, including third-party verification and GMP-compliant facilities. Natural Factors, for example, has been family-owned for over 60 years and subjects every batch to rigorous contaminant screening. For durable options, check our top durable digestive health supplements.
Final Thoughts
For most people seeking reliable acid reflux relief, Natural Factors DGL Licorice 400 mg offers a well-rounded, affordable chewable tablet with outstanding quality assurance. If you prefer a premium blend with additional herbal support, Pure Encapsulations DGL Plus, 60 Capsules combines DGL with aloe vera and marshmallow root for comprehensive digestive wellness.
Frequently Asked Questions
How does DGL licorice help with acid reflux?
DGL licorice supports the natural mucosal lining of the stomach and esophagus, which can help soothe irritation caused by acid reflux. It is deglycyrrhizinated to remove a compound that may affect blood pressure, making it safe for regular use.
What is the difference between DGL and regular licorice?
Regular licorice contains glycyrrhizin, which can cause side effects like elevated blood pressure when consumed in large amounts. DGL (deglycyrrhizinated licorice) has this compound removed, making it suitable for daily digestive support without the same risks.
How should I take DGL supplements for best results?
Most DGL supplements are taken 20 minutes before meals, one to three times daily. Chewable tablets should be chewed thoroughly, while capsules can be swallowed with water. Consistency is key for optimal digestive support in 2026.
Are there any side effects of DGL licorice?
DGL licorice is generally well-tolerated, but some individuals may experience mild bloating or changes in bowel movements. If you have a history of digestive issues, consult a healthcare professional before starting any new supplement. For more on digestive enzymes, see our best digestive enzyme supplements after gallbladder removal.
