If you have ever dealt with occasional heartburn, indigestion, or a general sense of stomach discomfort after meals, you know how much it can affect your day. Many people turn to deglycyrrhizinated licorice (DGL) as a gentle, plant based way to support a healthy stomach lining and overall digestive comfort. Unlike standard licorice, DGL has the compound glycyrrhizin removed, making it a safer choice for long term use. In this guide, we review eight of the top DGL supplements on the market, from trusted brands like Natural Factors, Pure Encapsulations, and Nutricost. Whether you prefer chewable tablets, capsules, or a liquid formula, we cover options for every need. For more on supporting your gut, check out our roundup of the best probiotic for men for bloating as a complementary approach.
Pros
- Specialized DGL formulation protects stomach lining without side effects of regular licorice
- Highly rated for digestive support, with a 4.9-star average from users
- Clean label: vegan, gluten-free, dairy-free, and free from major allergens
- Rigorous third-party testing for safety and purity
Cons
- Chewable tablets may not be suitable for those who dislike licorice flavor
- Requires consistent pre-meal timing for best results
- Limited to digestive health benefits; not a multi-purpose supplement
Natural Factors DGL Licorice 400 mg chewable tablets are a targeted digestive supplement designed for anyone seeking gentle, natural support for stomach and intestinal health. Unlike standard licorice root, this deglycyrrhizinated formula (DGL) removes glycyrrhizin, making it safe for long-term use without affecting blood pressure. It’s an excellent choice for individuals with occasional indigestion, heartburn, or those wanting to maintain a healthy gut lining.
The standout feature is the chewable form, which allows the active compounds to begin soothing the stomach immediately. Each tablet delivers 400 mg of DGL licorice extract, and taking one to three tablets 20 minutes before meals helps reinforce the mucosal barrier. Users report noticeable relief from discomfort, especially when taken consistently. The natural sweetness from licorice makes the tablets palatable, though the flavor may take some getting used to.
Build quality is impressive: Natural Factors, a family-owned company for over six decades, subjects every batch to ISURA third-party testing for more than 800 contaminants. The tablets are vegan, free from gluten, dairy, soy, and GMOs, which aligns with clean-label preferences. The 180-count bottle offers a two- to three-month supply at the recommended dosage, providing good value for daily use.
One potential drawback is the specific taste of licorice, which some may find strong or medicinal. Additionally, the product’s benefits are focused on digestive support; it’s not a broad-spectrum supplement. Users with severe conditions should consult a healthcare professional before use. However, for its intended purpose, the DGL formula stands out as a targeted, effective solution.
Overall, Natural Factors DGL Licorice 400 mg chewable tablets earn high marks for purity, efficacy, and clean formulation. If you’re looking for a gentle digestive aid that supports your stomach lining without additives or allergens, this supplement is a trustworthy choice. Its strong ratings and rigorous testing make it a top pick in the licorice root category.
Pros
- High potency 20:1 extract for maximum effectiveness per capsule.
- USDA Organic certified for premium quality.
- Long lasting supply with 120 capsules per bottle.
- Vegan and allergen free, suitable for many dietary needs.
- Produced in the USA with stringent quality control.
Cons
- No customer reviews yet to validate real world efficacy.
- Results may vary and consistent use is necessary for best outcomes.
- Not suitable for individuals with certain medical conditions or those taking specific medications without professional advice.
The Zazzee USDA Organic DGL Licorice 20:1 Extract is a high potency digestive supplement designed for those seeking natural, concentrated support. Ideal for individuals with occasional stomach discomfort or those wanting to maintain a healthy digestive lining, this extract offers a powerful alternative to standard powders.
Its standout feature is the 20:1 extract ratio, meaning each capsule delivers 20 times the active compounds of regular DGL powder. This allows for a simpler regimen, requiring just one capsule per serving. The USDA Organic certification further elevates its appeal, ensuring the product is free from synthetic pesticides and contaminants, with all ingredients including the capsule meeting organic standards.
Manufactured in a US based GMP certified facility, the build quality is excellent. The capsules are fully vegan and free from common allergens like gluten, soy, and dairy, making them accessible to a wide audience. The 120 count supply lasts for four months, offering substantial value for a premium organic product.
One potential drawback is the absence of customer reviews, which means individual experiences are yet to be widely shared. Additionally, as with any licorice supplement, users with hypertension or kidney issues should consult a healthcare provider before use. The product is designed for consistent, long term use to achieve optimal results.
Overall, Zazzee delivers a potent, pure, and ethically produced DGL supplement that stands out in the crowded market. For those prioritizing organic certification and high extract potency, this is an excellent choice that combines effectiveness with peace of mind.
Pros
- Potent 10:1 extract means a little goes a long way.
- Ample 120-serving supply for extended use without frequent repurchasing.
- Manufactured in a certified facility with third-party testing for purity.
- Gluten-free and non-GMO, suitable for various dietary needs.
- Trusted brand with transparent quality processes.
Cons
- New product with no customer reviews yet, so long-term feedback is limited.
- Capsules may be large for some users; check if you have difficulty swallowing pills.
- No flavored or chewable options available for those who dislike capsules.
Nutricost DGL Extract offers a potent 10:1 concentration of deglycyrrhizinated licorice root, delivering 500mg of extract per capsule. This supplement is designed for individuals seeking digestive support, particularly those who prefer a high-potency, standardized herbal extract. The 120-capsule bottle provides a two-month supply, making it convenient for daily use.
The standout feature is the 10:1 extraction ratio, which means each capsule contains the equivalent of 5,000mg of raw licorice root. This concentration enhances the beneficial compounds while removing glycyrrhizin, a component that can cause side effects. Real-world performance is backed by Nutricost's commitment to third-party testing and NSF-certified manufacturing, ensuring consistent potency and purity.
Build quality is solid: the capsules are standard size and the bottle is practical for storage. The product is gluten-free and non-GMO, appealing to clean-label advocates. However, as with any supplement, individual results may vary, and those with specific health conditions should consult a healthcare professional before use.
A potential drawback is the lack of customer reviews, which makes it harder to gauge broad user satisfaction. Additionally, some users may find the capsules large or prefer liquid or chewable alternatives. However, for those who prioritize potency and rigorous quality control, this is a compelling choice.
Overall, Nutricost DGL Extract stands out for its high concentration and transparent manufacturing. It is an excellent option for anyone looking for a reliable, potent digestive support supplement. The value is strong given the serving count, and the brand's reputation adds trust. If you are comfortable with capsules and want a concentrated extract, this product deserves consideration.
Pros
- High-quality, clean formula with no common allergens or artificial additives
- Combines multiple gut-soothing herbs for multi-faceted support
- Vegan and gluten-free, suitable for various dietary needs
- Trusted brand known for purity and potency
- Large 180-capsule bottle provides long-term value
Cons
- Premium price point may be higher than comparable products
- Capsules may be large for some users to swallow
- Limited customer reviews available, so real-world feedback is scarce
Pure Encapsulations DGL Plus is a targeted herbal supplement designed to support a healthy stomach lining and gastrointestinal tract. It is particularly suited for individuals seeking natural digestive support, especially those with sensitive stomachs or those looking to maintain gut health as part of their wellness routine.
The standout feature of this product is its comprehensive blend of deglycyrrhizinated licorice (DGL), aloe vera, marshmallow root, and slippery elm bark. DGL is well-known for its soothing properties, while the additional herbs work synergistically to provide comfort and support for the digestive system. This combination sets it apart from single-herb supplements and offers a more holistic approach to gut health.
In terms of design and build quality, Pure Encapsulations emphasizes purity and safety. The formula is vegan, gluten-free, and free from common allergens, artificial ingredients, and GMOs. The capsules are manufactured and tested to verify potency, ensuring that each dose delivers the intended benefits. The 180-count bottle offers a generous supply, making it convenient for daily use.
While there are no reported drawbacks from the limited reviews, the price point is higher than some competitors, which may be a consideration for budget-conscious buyers. Additionally, as with any supplement, individual results may vary, and it is always advisable to consult a healthcare professional before starting a new regimen.
Overall, Pure Encapsulations DGL Plus is a high-quality, well-formulated supplement for those prioritizing gut health. Its clean ingredient profile and comprehensive herbal blend make it a reliable choice for individuals seeking natural digestive support. Despite the premium cost, the product's purity and effectiveness justify the investment for many users.
Brand: Pure Encapsulations
Product Name: DGL Plus
Quantity: 180 Capsules
Form: Capsule
Dietary Features: Vegan, Gluten-Free, Non-GMO
Key Ingredients: Deglycyrrhizinated Licorice (DGL), Aloe Vera, Marshmallow Root, Slippery Elm Bark
Dimensions: 4.2 x 3.7 x 3.7 inches
Product Group: Drugstore
Pros
- Liposomal delivery may improve bioavailability of active compounds
- Multi-ingredient blend targets different aspects of digestive health
- Easy to use liquid dropper with customizable dosage
- DGL formula is gentler on the system than standard licorice root
- Plant-based and free from common allergens (check label for specifics)
Cons
- Some users may find the taste of liquid herbal extracts unpleasant
- Only 60 servings per bottle may require frequent reordering for daily users
- Limited customer reviews available to gauge real-world effectiveness
The HesperiIyntis Liposomal DGL Licorice Root Extract is a liquid dietary supplement designed to support digestive wellness. It is especially suited for individuals seeking a plant-based alternative to capsules or tablets, with a convenient dropper format that allows precise serving control. The formula combines deglycyrrhizinated licorice root with L-glutamine, marshmallow root, aloe vera, clove bud, slippery elm bark, and capsicum fruit for a broad-spectrum approach to gut health.
The standout feature is the liposomal delivery system using phosphatidylcholine from sunflower oil, which aims to enhance absorption of the botanical extracts. This liquid format is a practical choice for those who have difficulty swallowing pills or prefer customizable dosing. The removal of glycyrrhizin from the licorice root reduces the risk of side effects associated with standard licorice, such as potassium loss or blood pressure elevation, making it safer for long-term use.
In terms of design, the 4-ounce amber dropper bottle is compact and travel-friendly. Each drop is approximately 0.45-0.5 mL, and the recommended 4 drops provide a 2 mL serving. The product is free from artificial additives and is based on well-researched botanical ingredients. However, as a liquid herbal supplement, it may have a strong taste that some users find unpleasant. Mixing with water or juice could help mask the flavor.
A potential drawback is the limited number of servings per bottle (60 servings at the standard dose), which means regular users might need to repurchase frequently. Additionally, the product currently has no customer reviews, so individual experiences with effectiveness and taste are not yet available. Users should consult a healthcare professional before starting any new supplement, especially those with medical conditions or taking medications.
Overall, the HesperiIyntis Liposomal DGL Licorice Root Extract offers a well-rounded, liposomal liquid option for digestive support. Its multi-ingredient formula and thoughtful design make it a compelling choice for those looking to simplify their supplement routine. While the taste may be an acquired one and the serving size limited, the quality of ingredients and innovative delivery system justify consideration for anyone prioritizing gut health.
Pros
- Comprehensive herbal formula targeting gut lining health
- Clean, allergen-free ingredient profile suitable for sensitive individuals
- Vegan and gluten-free certification meets dietary restrictions
- Trusted brand with rigorous quality testing and expert formulation
Cons
- Some users may prefer tablets over capsules for ease of swallowing
- Limited user reviews available to gauge real-world effectiveness
- Higher price point compared to basic licorice root supplements
Pure Encapsulations DGL Plus is a targeted herbal supplement designed to support the health of your stomach lining and gastrointestinal tract. It combines deglycyrrhizinated licorice (DGL) with soothing botanicals like aloe vera, marshmallow root, and slippery elm bark. This makes it an excellent choice for individuals looking for gentle, plant-based digestive support, especially those with sensitive stomachs or dietary restrictions.
The standout feature of this formula is its use of DGL, which provides the benefits of licorice root without the compound glycyrrhizin, known to affect blood pressure. The addition of aloe vera, marshmallow root, and slippery elm bark further enhances mucosal comfort and soothes the digestive tract. While there are no user reviews available yet, the ingredient profile is well-regarded in herbal medicine for gut lining support.
In terms of design and build quality, Pure Encapsulations maintains a reputation for purity and potency. The capsules are vegan and gluten-free, and the product is free from common allergens, artificial ingredients, and GMOs. Each batch is tested to verify quality, giving users confidence in what they are consuming. The 60-count bottle offers a convenient one-month supply at the recommended dosage.
A potential drawback is the lack of consumer feedback, making it harder to assess real-world performance. Additionally, some users may find the price slightly higher than basic licorice root supplements, though the premium blend and rigorous testing justify the cost. The capsule form may not be ideal for those who prefer chewables or powders.
Overall, Pure Encapsulations DGL Plus is a well-formulated, clean-label supplement for those seeking targeted gut lining support. If you value quality ingredients and a brand committed to purity, this product is a solid choice. However, if you have specific health concerns, consulting a healthcare professional before use is always recommended.
Pros
- Liquid formulation may offer faster absorption compared to dry capsules
- Adaptogenic herbs add stress-relief benefits beyond basic licorice root
- Easy-to-swallow capsule design simplifies daily use
- Natural ingredients align with clean-label preferences
- Designed for long-term digestive comfort without harsh effects
Cons
- No customer reviews yet makes it hard to gauge real-world experience
- Sediment inside capsules may be off-putting to some users, though normal
- Price point is moderate compared to basic licorice root supplements
The HesperiIyntis DGL Licorice supplement is a thoughtfully formulated blend that goes beyond basic licorice root. Designed for those who experience occasional stomach discomfort linked to stress, it combines deglycyrrhizinated licorice (DGL) with adaptogens like ashwagandha, rhodiola, and holy basil. This makes it a dual-purpose product for digestive and emotional well-being, ideal for anyone looking to support their gut and stress levels in one daily capsule.
Standout features include its liquid-filled capsule format, which delivers a concentrated botanical extract without the need for multiple pills. The addition of adaptogens targets the gut-brain axis, offering a more holistic approach than standard DGL products. While performance data is limited due to zero reviews, the ingredient profile is grounded in traditional herbal use and modern adaptogenic research, promising a gentle yet effective routine for everyday stomach comfort.
Build quality appears solid: the capsules are easy to swallow and the liquid formula ensures consistent dosing. HesperiIyntis emphasizes natural botanical quality, noting that slight sediment may form inside the capsules over time. This is a normal characteristic of plant extracts and does not impact potency or safety, though it may surprise new users.
Potential drawbacks include the lack of customer feedback, which makes it difficult to assess real-world results. Additionally, the adaptogen blend may not appeal to purists wanting only licorice root. The price is reasonable given the dual-action formula, but budget-conscious shoppers might find cheaper alternatives with simpler ingredients.
Overall, this DGL licorice capsule is a well-conceived option for those seeking a comprehensive digestive support that also addresses stress-related triggers. It is best suited for individuals who value botanical synergy and convenience. If you're open to a multi-ingredient approach, HesperiIyntis offers a promising addition to your daily wellness routine.
Buying Guide
Form and Convenience
DGL supplements come in several formats, including chewable tablets, capsules, and liquid drops. Chewable tablets are a classic choice, often flavored to make them pleasant to take before meals. Capsules offer a straightforward, no taste option, while liquid formulas can be mixed into water or taken directly. Your lifestyle and preferences will guide the best pick. If you travel often, capsules might be more portable. For a deeper look at digestive aids in different forms, explore our best digestive enzymes pills guide.
Potency and Extract Ratio
Many DGL products highlight their extract concentration, such as a 10:1 or 20:1 ratio. A higher ratio means the extract is more concentrated, so you may need fewer capsules per serving. However, the optimal potency depends on your individual needs and how your body responds. Always check the serving size and the amount of DGL per dose to ensure you are getting an effective amount. Some products also blend DGL with complementary herbs like marshmallow root or aloe vera for added soothing benefits.
Quality and Purity Standards
Because supplements are not strictly regulated by the FDA, choosing a brand that prioritizes quality is crucial. Look for products that are third party verified for purity and potency. Some brands go a step further with USDA Organic certification, which ensures the ingredients are grown without synthetic pesticides or fertilizers. Vegan and gluten free labels are also common and helpful if you have dietary restrictions. For more on what to look for in a quality supplement, visit the Digestive Health category page.
Additional Ingredients and Blends
Some DGL supplements are standalone, while others combine DGL with other gut soothing botanicals like slippery elm, aloe vera, or L glutamine. These blends can offer broader support for the stomach lining and digestive tract. If you are looking for a comprehensive formula, a multi ingredient product might be a better fit. On the other hand, if you prefer to keep your supplement routine simple, a pure DGL extract could be ideal. For a deeper dive into digestive enzyme blends, see our BIOptimizers MassZymes review.
Final Thoughts
After reviewing the top contenders, we believe the Natural Factors DGL Licorice 400 mg stands out for its high rating, vegan chewable format, and rigorous third party verification, making it an excellent choice for daily digestive support. For those seeking a potent, organic option in capsule form, the Zazzee USDA Organic DGL Licorice 20:1 Extract offers a concentrated 20:1 extract with a four month supply, ideal for value conscious users who prioritize organic ingredients. Both products deliver reliable stomach comfort, but your choice will depend on whether you prefer chewables or capsules.
Frequently Asked Questions
What is DGL and how does it differ from regular licorice?
DGL stands for deglycyrrhizinated licorice. The glycyrrhizin compound, which can cause side effects like elevated blood pressure, is removed. This makes DGL safer for daily use while still providing soothing support for the stomach lining.
When is the best time to take a DGL supplement?
Most DGL products are best taken 15 to 20 minutes before meals. This allows the supplement to coat and soothe the stomach lining in preparation for digestion. Always follow the specific instructions on the product label.
Can I take DGL with other digestive supplements?
Yes, DGL is often combined with probiotics, digestive enzymes, or other herbal supplements for comprehensive gut health. If you are unsure about interactions, consult a healthcare professional. For budget friendly enzyme options, see our best digestive enzymes under $10 guide.
Is DGL safe for long term use?
Because the glycyrrhizin is removed, DGL is considered safe for extended use by most adults. However, if you have a medical condition or are pregnant or nursing, it is wise to speak with your doctor before starting any new supplement regimen.
