If you have ever dealt with occasional heartburn, bloating, or a sensitive stomach, you have likely wondered which herbal ally is best. Two of the most talked-about natural remedies are DGL (deglycyrrhizinated licorice) and marshmallow root. Both are rooted in traditional wellness, but they work in distinct ways to calm your digestive tract. This guide breaks down how they differ and which one might suit your needs better in 2026. We also look at two popular products that combine these ingredients with other gut-friendly botanicals, so you can make an informed choice without confusion. For more background on how other gut supports stack up, check out our comparison of L glutamine vs DGL.

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Best Seller

Liposomal DGL Licorice Root Extract

HesperiIyntis
9.6 /10
AI Score
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This liposomal liquid supplement combines DGL licorice extract with L-glutamine, marshmallow root, aloe vera, and other botanicals for digestive support. Its sunflower-based liposomal delivery and convenient dropper bottle make it ideal for those seeking a plant-based, easy-to-take digestive aid.
Pros & Cons

Pros

  • Liposomal delivery may improve bioavailability of active compounds
  • Multi-ingredient blend targets different aspects of digestive health
  • Easy to use liquid dropper with customizable dosage
  • DGL formula is gentler on the system than standard licorice root
  • Plant-based and free from common allergens (check label for specifics)

Cons

  • Some users may find the taste of liquid herbal extracts unpleasant
  • Only 60 servings per bottle may require frequent reordering for daily users
  • Limited customer reviews available to gauge real-world effectiveness
Detailed Review

The HesperiIyntis Liposomal DGL Licorice Root Extract is a liquid dietary supplement designed to support digestive wellness. It is especially suited for individuals seeking a plant-based alternative to capsules or tablets, with a convenient dropper format that allows precise serving control. The formula combines deglycyrrhizinated licorice root with L-glutamine, marshmallow root, aloe vera, clove bud, slippery elm bark, and capsicum fruit for a broad-spectrum approach to gut health.

The standout feature is the liposomal delivery system using phosphatidylcholine from sunflower oil, which aims to enhance absorption of the botanical extracts. This liquid format is a practical choice for those who have difficulty swallowing pills or prefer customizable dosing. The removal of glycyrrhizin from the licorice root reduces the risk of side effects associated with standard licorice, such as potassium loss or blood pressure elevation, making it safer for long-term use.

In terms of design, the 4-ounce amber dropper bottle is compact and travel-friendly. Each drop is approximately 0.45-0.5 mL, and the recommended 4 drops provide a 2 mL serving. The product is free from artificial additives and is based on well-researched botanical ingredients. However, as a liquid herbal supplement, it may have a strong taste that some users find unpleasant. Mixing with water or juice could help mask the flavor.

A potential drawback is the limited number of servings per bottle (60 servings at the standard dose), which means regular users might need to repurchase frequently. Additionally, the product currently has no customer reviews, so individual experiences with effectiveness and taste are not yet available. Users should consult a healthcare professional before starting any new supplement, especially those with medical conditions or taking medications.

Overall, the HesperiIyntis Liposomal DGL Licorice Root Extract offers a well-rounded, liposomal liquid option for digestive support. Its multi-ingredient formula and thoughtful design make it a compelling choice for those looking to simplify their supplement routine. While the taste may be an acquired one and the serving size limited, the quality of ingredients and innovative delivery system justify consideration for anyone prioritizing gut health.

Buying Guide

Assess Your Primary Digestive Concern

The first step is identifying what bothers you most. DGL is well-regarded for supporting the stomach lining, especially when occasional discomfort strikes after meals. Marshmallow root, on the other hand, is known for its mucilaginous quality. It forms a gentle coating that can soothe areas along the digestive tract from the throat to the intestines. If your main issue is upper stomach or esophageal sensitivity, DGL might be more targeted. For lower gut or general coating support, marshmallow root could be the better fit. Some individuals benefit from both, which is why combination formulas are popular.

Consider the Format of Your Supplement

The delivery method matters for both effectiveness and convenience. Liquids and liposomal formulations, like the Liposomal DGL Licorice Root Extract, may offer faster absorption. They are easy to adjust by drop and can be taken on the go. Gummies, such as the Sugar Free DGL Stomach Smoother Gummies, provide a chewable, pre-measured option that tastes pleasant and fits easily into a daily routine. If you dislike swallowing pills or struggle with compliance, a gummy format could help you stay consistent. For a deeper look at how another gut hero compares, read zinc carnosine vs L-Glutamine.

Check for Added Botanicals and Nutrients

Many modern gut formulas blend DGL and marshmallow root with other complementary ingredients like slippery elm, aloe vera, L-glutamine, probiotics, and prebiotics. These additions can amplify the benefits by addressing multiple aspects of digestive health. For example, probiotics and prebiotics support the microbiome, while L-glutamine aids gut lining repair. If you prefer a comprehensive approach, look for a multi-ingredient product that includes both DGL and marshmallow root. However, if you want to keep things simple or avoid specific botanicals, a standalone option might be better. Learn more about L glutamine vs slippery elm for another pairing.

Evaluate Dietary Preferences and Restrictions

Both products we reviewed are plant-based. The Liposomal DGL is a liquid formula that uses sunflower lecithin and is free from common allergens. The Sugar Free DGL Gummies are also suitable for those avoiding sugar and include no artificial colors. Always check labels for ingredients that might conflict with your diet, such as gluten, soy, or animal-derived components. If you have specific allergies or follow a strict regimen, this step will guide you to a safe choice.

Final Thoughts

Choosing between DGL and marshmallow root does not have to be a solo decision. Both ingredients can work together in carefully crafted supplements. If you value rapid absorption and a versatile liquid that combines seven botanicals plus L-glutamine, Liposomal DGL Licorice Root Extract, Digestive by HesperiIyntis is a strong candidate. If you prefer a tasty, sugar-free gummy that includes probiotics, prebiotics, and a comprehensive blend of gut-soothing ingredients including both DGL and marshmallow root, Sugar Free DGL Stomach Smoother Gummies with DGL by NutraPerfecto offers an easy daily ritual. Your gut will thank you for taking the time to match your unique needs with the right formula.

Frequently Asked Questions

Can I take DGL and marshmallow root together?
Yes, many supplements combine them, as DGL supports the stomach lining while marshmallow root provides a soothing coating. This synergy may enhance overall digestive comfort and is safe for most adults when taken as directed.

How long does it take for DGL or marshmallow root to work?
Some people notice relief within minutes, especially with DGL for immediate heartburn. For chronic issues, consistent daily use over a few weeks is often needed to see lasting benefits, as the ingredients gently support tissue health.

Are there any side effects from DGL or marshmallow root?
Both are generally well-tolerated. DGL has the glycyrrhizin removed, so it does not affect blood pressure like standard licorice. Marshmallow root may slow the absorption of other medications, so separate them by at least one hour.

Which is better for acid reflux: DGL or marshmallow root?
DGL is often preferred for acid reflux due to its ability to support the esophageal sphincter and stomach lining. But marshmallow root can soothe irritation in the throat and esophagus. Many people use both for comprehensive relief. Explore more on this topic in our COMPARISONS category.

Still curious about how other gut supports compare?

Read our analysis of L glutamine vs collagen for gut health to round out your knowledge.