You are eating well and exercising, but your gut still feels off. Bloating, irregularity, or occasional discomfort can make you wonder if your digestive system needs extra support. Two popular ingredients often appear in gut health formulas: L glutamine and DGL (deglycyrrhizinated licorice). But which one works better? And can they be combined for greater effect? In this guide, we explore the differences between L glutamine vs DGL, and we spotlight a comprehensive formula that brings them together. We will also discuss how to choose the right gut support supplement for your needs.
If you are curious about other gut health comparisons, check out our article on L glutamine vs probiotics for gut health.
Pros
- All-in-one formula targeting multiple aspects of gut health.
- High-potency probiotic blend with four shelf-stable strains.
- Vegan, non-GMO, and allergen-friendly ingredient profile.
- Manufactured in a cGMP-certified USA facility.
- Contains organic and fermented prebiotics to enhance probiotic effectiveness.
Cons
- As a newer product, real-world feedback on long-term efficacy is still limited.
- DGL licorice root may interact with certain medications, so medical consultation is advised.
- 90 capsules per bottle may require frequent repurchase for users needing higher daily doses.
The Amen Leaky Gut supplement is a thoughtfully designed formula for those seeking comprehensive digestive support. It combines L-glutamine, DGL licorice, zinc, organic turmeric, and marshmallow root in a convenient vegan capsule, making it easy to add to your daily routine.
What sets this supplement apart is its inclusion of 10 billion CFU of shelf-stable probiotics from four distinct strains, along with organic prebiotics like apple cider vinegar and ginger. This blend works synergistically to support a balanced gut microbiome and a healthy intestinal lining, addressing both immediate and long-term gut health needs.
The formulation is built around high-quality ingredients, including L-glutamine for gut barrier repair and DGL licorice root that has been processed to remove glycyrrhizin, minimizing the risk of side effects. It is also vegan, non-GMO, and free from major allergens, which broadens its appeal to health-conscious consumers with dietary restrictions.
One potential drawback is the limited real-world feedback available, making it difficult to gauge long-term results. Additionally, the 90-capsule bottle may not offer the best value for those requiring higher daily doses, and the licorice root extract, even in DGL form, might interact with certain medications. Consulting a healthcare provider before use is recommended.
Overall, Amen Leaky Gut is a well-rounded, high-quality supplement that delivers a comprehensive approach to gut health. Its clean ingredient profile, probiotic blend, and supportive nutrients make it a strong candidate for anyone looking to fortify their digestive system, provided they are mindful of serving size and potential interactions.
Pros
- Specialized DGL formulation protects stomach lining without side effects of regular licorice
- Highly rated for digestive support, with a 4.9-star average from users
- Clean label: vegan, gluten-free, dairy-free, and free from major allergens
- Rigorous third-party testing for safety and purity
Cons
- Chewable tablets may not be suitable for those who dislike licorice flavor
- Requires consistent pre-meal timing for best results
- Limited to digestive health benefits; not a multi-purpose supplement
Natural Factors DGL Licorice 400 mg chewable tablets are a targeted digestive supplement designed for anyone seeking gentle, natural support for stomach and intestinal health. Unlike standard licorice root, this deglycyrrhizinated formula (DGL) removes glycyrrhizin, making it safe for long-term use without affecting blood pressure. It’s an excellent choice for individuals with occasional indigestion, heartburn, or those wanting to maintain a healthy gut lining.
The standout feature is the chewable form, which allows the active compounds to begin soothing the stomach immediately. Each tablet delivers 400 mg of DGL licorice extract, and taking one to three tablets 20 minutes before meals helps reinforce the mucosal barrier. Users report noticeable relief from discomfort, especially when taken consistently. The natural sweetness from licorice makes the tablets palatable, though the flavor may take some getting used to.
Build quality is impressive: Natural Factors, a family-owned company for over six decades, subjects every batch to ISURA third-party testing for more than 800 contaminants. The tablets are vegan, free from gluten, dairy, soy, and GMOs, which aligns with clean-label preferences. The 180-count bottle offers a two- to three-month supply at the recommended dosage, providing good value for daily use.
One potential drawback is the specific taste of licorice, which some may find strong or medicinal. Additionally, the product’s benefits are focused on digestive support; it’s not a broad-spectrum supplement. Users with severe conditions should consult a healthcare professional before use. However, for its intended purpose, the DGL formula stands out as a targeted, effective solution.
Overall, Natural Factors DGL Licorice 400 mg chewable tablets earn high marks for purity, efficacy, and clean formulation. If you’re looking for a gentle digestive aid that supports your stomach lining without additives or allergens, this supplement is a trustworthy choice. Its strong ratings and rigorous testing make it a top pick in the licorice root category.
Pros
- High-purity ingredients from a trusted brand with cGMP manufacturing
- Dual-action support for both workout performance and post-exercise recovery
- Easy to mix and consume, with no strong taste or artificial additives
- Suitable for vegan and gluten-free dietary needs
- Economical bundle that saves money over separate purchases
Cons
- Unflavored formula may not appeal to users who prefer a flavored supplement
- Large 400g tubs can be bulky for storage or travel
- No customer reviews yet, so long-term user feedback is limited
The ALLMAX Creatine Monohydrate and L-Glutamine Powder Stack is a targeted bundle for athletes and fitness enthusiasts who want to simplify their supplement routine. It combines two foundational ingredients: creatine for explosive strength and power, and glutamine for muscle recovery and reduced soreness. This stack is designed for anyone engaged in high-intensity training, from beginners to advanced lifters.
Standout features include the unflavored, easy-mix formula that dissolves cleanly in water, juice, or protein shakes without clumping or leaving a gritty texture. The creatine monohydrate helps replenish ATP levels during intense sets, while the L-glutamine supports faster recovery and may ease post-workout discomfort. Both ingredients are free from added sugars, fillers, and artificial flavors, making them a pure choice for clean supplementation.
In terms of build quality, ALLMAX is a well-known brand in sports nutrition, and this product is manufactured according to current Good Manufacturing Practices (cGMP). The powder is vegan and gluten-free, catering to a wide range of dietary preferences. Each tub holds 400 grams, providing a generous supply that can last several weeks depending on serving size.
A potential drawback is that the unflavored powder may not appeal to those who prefer a sweet or flavored drink. Additionally, the large tubs are not the most portable option for gym bags or travel. Since there are no customer reviews at this time, first-time buyers will need to rely on the brand's reputation and product specifications.
Overall, the ALLMAX Creatine Monohydrate + L-Glutamine Powder Stack delivers a practical and cost-effective way to support both performance and recovery. It is a solid choice for athletes who value purity, simplicity, and value. With its clean ingredient profile and trusted manufacturing, this stack earns a strong recommendation for anyone looking to enhance their training results.
Pros
- Convenient gummy form that eliminates the need for capsules or powders.
- Comprehensive blend of botanicals and nutrients for digestive health.
- High customer rating of 4.8 out of 5 stars (based on early reviews).
- Pectin-based formula suitable for various dietary preferences.
- Pineapple flavor makes daily supplementation enjoyable.
Cons
- Limited customer reviews available to verify long-term effectiveness.
- Contains DGL from licorice root; may not be suitable for individuals with certain medical conditions without consulting a doctor.
- Price point is higher than some basic DGL supplements on the market.
The Geloyar DGL Gummies are a multi-ingredient supplement designed to promote stomach comfort and digestive wellness. This product is ideal for adults who experience occasional discomfort after heavy meals or during busy schedules and prefer a convenient gummy format over traditional pills.
The standout feature is the blend of 1200 mg DGL, 75 mg zinc L-carnosine, and 150 mg slippery elm bark extract per serving. These ingredients work together to support the stomach lining and provide soothing relief. The addition of PHGG and sodium alginate further enhances the formula with soluble fiber and alginate components.
The gummies are pectin-based with a pleasant pineapple flavor, making them easy to chew and digest. They require no water or mixing, fitting seamlessly into morning, workday, or evening routines. The packaging is straightforward, with 120 gummies per bottle for a two-month supply.
One potential drawback is the lack of extensive customer reviews to confirm long-term benefits. Additionally, the inclusion of DGL from licorice root may require caution for those with high blood pressure or kidney issues. It is advisable to consult a healthcare provider before use.
Overall, the Geloyar DGL Gummies offer a well-rounded, convenient option for digestive support. With a strong 4.8 rating and a thoughtful ingredient profile, they are a solid choice for individuals seeking an easy-to-take stomach comfort supplement.
Brand: Geloyar
Form: Pectin-based gummy
Flavor: Pineapple
Count: 120 gummies per bottle
Serving Size: 2 gummies
Key Ingredients: DGL (1200 mg), Zinc L-Carnosine (75 mg), Slippery Elm Bark Extract (150 mg), Marshmallow Root Extract (150 mg), PHGG, Sodium Alginate
Color: Yellow
Weight: 0.44 pounds
Product Group: Drugstore
Pros
- High purity with no unnecessary additives
- Generous 194 servings per container for extended use
- Easy to mix and consume after workouts
- Trusted brand with decades of experience in sports nutrition
- Neutral taste blends well with other drinks
Cons
- Some users may prefer flavored options for taste
- Requires a shaker cup for best mixing results
- Large container size may not be ideal for travel
Optimum Nutrition L-Glutamine Muscle Recovery Powder is a high-quality supplement designed to help your muscles recover after strenuous exercise. Each serving delivers 5 grams of pure L-glutamine, an amino acid that plays a key role in muscle repair and immune function. This product is ideal for athletes, bodybuilders, and fitness enthusiasts looking to speed up recovery and reduce muscle soreness.
The standout feature of this supplement is its simplicity and purity. With 194 servings per 2.21 lb container, it offers excellent value for regular users. The powder mixes easily with water or your favorite beverage using a shaker cup, making it convenient to take right after your workout. Optimum Nutrition's reputation for quality is backed by over 35 years in the industry, so you can trust the product's consistency.
In terms of design, the container is practical and portable, fitting easily into a gym bag. The powder has a fine texture that dissolves quickly without clumping. There are no artificial flavors or colors, which is a plus for those who prefer a clean supplement. However, the unflavored taste might not appeal to everyone, and some may want to mix it with a flavored drink for better palatability.
One potential drawback is that the product comes in a large tub, which may not be travel-friendly. Additionally, while glutamine is beneficial for recovery, results can vary based on individual diet and training intensity. It's also worth noting that this supplement is best used as part of a comprehensive nutrition plan, not as a standalone solution.
Overall, Optimum Nutrition L-Glutamine Muscle Recovery Powder is a solid choice for anyone serious about post-workout recovery. Its high purity, ease of use, and generous serving size make it a practical addition to your fitness routine. If you're looking for a reliable, no-frills glutamine supplement, this product delivers on its promises.
Buying Guide
Ingredient Synergy
When comparing L glutamine vs DGL, look for a supplement that combines both ingredients for complementary benefits. L glutamine is a key amino acid that supports the intestinal lining, while DGL soothes and protects the gut mucosa. A formula like Amen Leaky Gut+ includes both, along with zinc, organic turmeric, and marshmallow root. This synergy can address multiple aspects of gut health at once.
For more on how different supplements work together, see our guide on Fiber Supplements vs Prebiotics.
Probiotic and Prebiotic Support
A robust gut health supplement should include probiotics and prebiotics to foster a balanced microbiome. Amen Leaky Gut+ delivers 10 billion CFU of shelf-stable probiotics with four strains, plus organic prebiotics like apple cider vinegar, ginger, and turmeric. This dual approach helps maintain beneficial bacteria while the L glutamine and DGL repair and protect the gut lining.
Quality and Purity
Choose supplements made with high quality, non GMO ingredients and free from common allergens. Amen Leaky Gut+ is vegan, gluten free, and free from soy, milk, egg, wheat, and shellfish. It is manufactured in the USA in a cGMP certified facility, ensuring you get a pure and potent product.
Form and Convenience
Consider whether you prefer capsules or powder. The Amen formula comes in capsules that can be taken with or without food, making it easy to integrate into your daily routine. This convenience can help you stay consistent, which is key for gut health improvements.
Final Thoughts
After examining the role of L glutamine vs DGL, we recommend Amen Leaky Gut, L-Glutamine, DGL Licorice as an excellent all in one choice for those seeking comprehensive gut support. This formula combines L glutamine, DGL, probiotics, prebiotics, and zinc in one capsule. For anyone focused on repairing and soothing their gut lining while boosting beneficial bacteria, this supplement covers all bases.
Frequently Asked Questions
Can I take L glutamine and DGL together?
Yes, many gut health supplements like Amen Leaky Gut+ combine L glutamine and DGL for synergistic benefits. L glutamine supports intestinal lining repair, while DGL soothes irritation. Taking them together can enhance overall gut health.
What is the difference between L glutamine and DGL?
L glutamine is an amino acid that helps maintain the integrity of the gut barrier, while DGL is a deglycyrrhizinated extract of licorice root that soothes mucosal tissues. They work through different mechanisms but complement each other.
How long does it take for L glutamine and DGL to work?
Results vary, but many people notice improvements in gut comfort within a few weeks of consistent use. For best results, combine supplementation with a balanced diet and healthy lifestyle.
Are there any side effects of L glutamine or DGL?
L glutamine is generally well tolerated, though high doses may cause mild digestive upset. DGL is processed to remove glycyrrhizin, which reduces the risk of side effects like blood pressure changes. Always consult your healthcare provider before starting any new supplement.
